Histone modifications: Now summoning sumoylation

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Histone modifications: Now summoning sumoylation.

H istones can be modified in many ways to affect gene expression, including acetylation deacetylation (1), phosphorylation (2), methylation (3), and ubiquitylation (4). Now, in this issue of PNAS, Shiio and Eisenman (5) report that sumoylation is yet another histone modification, and, interestingly, it may regulate transcriptional repression. Although there may appear to be a bewildering array ...

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ژورنال

عنوان ژورنال: Proceedings of the National Academy of Sciences

سال: 2003

ISSN: 0027-8424,1091-6490

DOI: 10.1073/pnas.2436173100